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Seminars
Join our complimentary seminars and learn about the latest technologies
in protein functional research and lentiviral gene delivery from
Clontech.
After the seminars, the speakers as well as Dr Hiroaki
Sagawa, Vice President of Research and Development, Clontech
Laboratories,
Inc. will be available to discuss how your research can benefit
from Clontech’s new technologies.
ProteoTuner™: A Novel Ligand-Dependant and RNAi-complementary
System for the Rapid and Direct Modulation of a Protein’s
Abundance in Cells
Clontech Laboratories, together with the laboratory of Dr. Tom
Wandless at Stanford University, have developed a new technology
called ProteoTuner™, which allows the amount of any recombinant
protein expressed in a cell to be rapidly, reversibly, and directly
controlled by a membrane permeable ligand. ProteoTuner, especially
if combined with RNAi, provides a powerful strategy for studying
protein function by allowing an endogenous protein to be replaced
by a recombinant one, whose level can be easily adjusted and
controlled.
Read the full abstract
Speaker: Michael Haugwitz, Ph.D.
Associate Director for Cell Biology, Clontech Laboratories, Inc.,
CA, US
High Lentiviral Titers Using a Novel 4th Generation Packaging
System
Clontech has developed an advanced lentiviral expression system
that provides the broad cellular tropism of VSV-G pseudotyped
lentivirus, extremely high viral titers, and excellent transgene
expression. Clontech’s Lenti-X™ Systems can be used
for consti¬tutive PCMV-based expression; for inducible Tet-On® or
Tet-Off® Advanced expression; or for expressing your recombinant
protein fused to a Living Colors® Fluorescent Protein. This
new lentiviral vector system , together with a 4th generation
packaging system, consistently produce lentiviral supernatants
having titers of up to 5x108 ifu/ml. This combination significantly
increases viral titer without increasing the risk of producing
replication competent lentivirus.
Read the full abstract
Speaker : Thomas P. Quinn, M.S.
Research Scientist, Viral Technologies Group, Clontech Laboratories,
Inc., CA, US
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